Adjusted likelihood approach to estimate the proportion of true null hypotheses in multiple tests
Keywords:
Multiple testing, likelihood approach, false discovery ratesAbstract
A number of methods have been established to estimate the proportion true null hypotheses in multiple testing
under the assumption of independency. On other hand, the test statistics are either discrete or continuous. In this
paper, we will review an existing likelihood approach for estimating the proportion of true nulls
controlling the false discovery rates when the test statistics are continuous (see Hualing and Hanfeng, 2021). We
therefore present an extension of these method that can successfully make some improvement of the
performance. Simulation study demonstrates that the new estimator performs very well.
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